Effects of Shear Injury on the Subsynovial Connective Tissue and Median Nerve within the Rabbit Carpal Tunnel: A Potential Animal Model of Carpal Tunnel Syndrome

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INTRODUCTION The synovial tissues in the carpal tunnel are unique in containing a substantial, multilayered subsynovial connective tissue (SSCT) and normally, the SSCT loosely connects the flexor tendons and median nerve. We tested the basic premise of our hypothesis, i.e. SSCT injury leads to progressive SSCT fibrosis and subsequent median neuropathy, by investigating the effect of a surgically induced shear injury to the SSCT on SSCT fibrosis and median nerve function in a rabbit model.

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تاریخ انتشار 2010